VICARIOUS NUCLEOPHILIC SUBSTITUTION OF HYDROGEN

REVIEWS
  1. M. M±kosza, W. Danikiewicz, K. Wojciechowski, "Vicarious Nucleophilic Substitution with Sulfur Containing Carbanions" Phosphorus, Sulfur, and Silicon 1990, 53, 457.
  2. M. M±kosza, K. Wojciechowski "Applications of Vicarious Nucleophilic Substitution in Organic Synthesis" Liebigs Ann. Chem. 1997, 1805-1816.
  3. M. M±kosza, K. Wojciechowski "Nucleophilic Aromatic Substitution of Hydrogen as a Tool for the Synthesis of Indole and Quinoline Derivatives" Heterocycles 2001, 54, 445-474
  4. K. Wojciechowski "1,3-Dihydro-2,1-benzisothiazole 2,2-Dioxides (Benzosultams) in Organic Synthesis" Heterocycles 2002, 57, 1717-1740.
  5. M. M±kosza, K. Wojciechowski "Nucleophilic Substitution of Hydrogen in Heterocyclic Chemistry" Chem. Rev. 2004, 104, 2631-2666.
  6. M. M±kosza, K. Wojciechowski "Reactions of nucleophiles with nitroarenes: Efficient synthetic routes to indoles" in SELECTED METHODS FOR SYNTHESIS AND MODIFICATION OF HETEROCYCLES, vol. III (V.G. Kartsev Editor), IBS Press, Moscow 2004, 103-139 (Book chapter).

Indoles from 3-nitrophenylisonitriles

K. Wojciechowski, M. M±kosza, "New Synthesis of Indole Derivatives via Vicarious Nucleophilic Substitution of Hydrogen"  Tetrahedron Lett., 1984, 25, 4793.


Synthesis of 1,3-dihydro-2,1-benzisothiazoline 2,2-dioxides

M. M±kosza, K. Wojciechowski, "Intramolecular Vicarious Nucleophilic Substitution of Hydrogen" Tetrahedron Lett. 1984, 25, 4791
K. Wojciechowski, M. M±kosza "Synthesis of Benzosultams via Intramolecular Vicarious Nucleophilic Substitution of Hydrogen" Synthesis 1992, 571


M. M±kosza, W. Danikiewicz, K. Wojciechowski, "Reactions of a­Chloroalkyl Sulfones with Nitronaphthalene Derivatives" Liebigs Ann. Chem. 1987,
     711.


Synthesis of hydroxyindole derivatives

4-Methoxyindole



5-Hydroxy- and 5-methoxyindole



6-Methoxyindole



7-Methoxyindole

M. M±kosza, W. Danikiewicz, K. Wojciechowski, "Simple and General Synthesis of Hydroxy­ and Methoxyindoles via Vicarious Nucleophilic
     Substitution of Hydrogen" Liebigs Ann. Chem. 1988, 203.


VNS in 5- and 6-nitroindoles

K. Wojciechowski, M. M±kosza, "Vicarious Nucleophilic Substitution in 5­ and 6­Nitroindole Derivatives" Synthesis 1989, 106.


Boulton-Katritzky rearrangement

S. Ostrowski, K. Wojciechowski, "Vicarious Nucleophilic Substitution of Hydrogen in Nitrobenzofuroxanes and the Boulton­Katritzky Rearrangement of the VNS products" Can. J. Chem. 1990, 68, 2239.


VNS with dichloroacetate carbanion

M. M±kosza, K. Sienkiewicz, K. Wojciechowski, "Vicarious Nucleophilic Substitution of Hydrogen in Nitroarenes by Carbanions of Alkyl
Dichloroacetates. Some New Transformations of Chloro(nitroaryl)acetates" Synthesis 1990, 850.


VNS in azulene

K. M±kosza, R. Kuciak, K. Wojciechowski "Vicarious Nucleophilic Substitution of Hydrogen in Azulenes" Liebigs Ann. Chem. 1994, 615.


Synthesis of benzo[c,d]indole framework

M. M±kosza, J. Stalewski, K. Wojciechowski, W. Danikiewicz "Synthesis of 1,3,4,5-Tetrahydrobenz[cd]indole via the Vicarious Nucleophilic
     substitution of Hydrogen", Tetrahedron, 1997, 53, 193-214.


Intramolecular VNS in pyridine and quinoline N-oxides

K. Wojciechowski, S. Kosiński "Synthesis of Novel Isothiazolo[4,3-b]-pyridine and Isothiazolo[4,3-b]quinoline Derivatives" Tetrahedron 2001, 57, 5009-5014.


VNS of the in situ generated 3-chlorobenzosultam

K. Wojciechowski, H. Modrzejewska "Vicarious Nucleophilic Substitution of Hydrogen in Nitroarenes with Carbanions of in situ Generated 1-Alkyl-3-chloro-1,3-dihydro-2,1-benzisothiazole 2,2-Dioxides" Synthesis 2003, 1503-1505.


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