CARBOHYDRATE-CONTAINING DENDRIMERS
N.D.Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences,
A new class of synthetic highly branched oligomeric molecules that can be prepared by reiteration of a few reaction sequences, the so-called dendrimers, has emerged since the 1980s [1] and currently dendrimers are known with units built of purely organic and organometallic compounds [2], nucleotides [3] and peptides [4]. Quite naturally, carbohydrate chemistry did not stand apart from this modern and attractive field of science (see, e.g., [5]). The immense diversity of carbohydrate-containing dendrimers stems from the variety of carbohydrate constituents, the mode of their incorporation and the core structures. Examples will be given of different synthetic strategies aimed at the assembly of these well-defined macromolecules and biological activities of selected glycodendrimers.
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