New macrocycles with planar chirality

Jarosław Kalisiak^a, Janusz Jurczak^a,b

^a Institute of Organic Chemistry, Polish Academy of Sciences, Warsaw, Poland

^b Department of Chemistry, Warsaw University, Poland

Structural studies of molecules possessing an element of planar chirality have started in 1940's with the synthesis and resolution of 1,12-dioxa[12]paracyclophane.¹ The interest in the synthesis of planar-chiral compounds has been rapidly growing since they are used as ligands for transition metal complexes.² The following question arises: could simple intraannular-arm macrocyclic system exist in enantiopure stable forms?